The crash happened early Saturday morning when a four door Nissan slammed into a concrete pillar near the 5 Freeway and N. San Fernando Blvd. in Burbank, authorities said.
Savannah Underwood, 18, managed to escape the vehicle.
She was taken to an area hospital with a broken leg and other injuries, but was expected to survive, according to Burbank Police Sgt. Darin Ryburn.
“This was a tough one. I’ve been here 28 years and the five fatalities is pretty rough,” Sgt. Ryburn said during a news conference.
Speed was a factor in the wreck, Sgt. Ryburn added.
The five deceased victims, all in their late teens and early twenties, were graduates of Burbank High and John Burroughs High, their friends told KTLA 5.
Underwood graduated from Options For Youth Charter High in Burbank earlier this year, according to her friends.
A growing memorial has been set up at the crash site to remember the victims.