Authorities were searching for the gunman after two pedestrians were wounded in Pacoima on Friday in a drive-by shooting that is likely gang-related, police said.
Officers originally responded to reports of a fatal injury near the intersection of Van Nuys and Glenoaks boulevards around 8 p.m., said Officer Drake Madison with the Los Angeles Police Department.
One of the victims was pronounced dead at the scene, while the other was taken to a nearby hospital for treatment and expected to survive, Madison said.
Video from the scene showed crime scene tape erected around the parking lot of a strip mall on the corner. A seafood restaurant called Mariscos La Bocana had a window shot out.
The shooter was traveling in a black vehicle with tinted windows and had not been apprehended, officials said.
Investigators were working to gather further information and compile a more specific description of the suspect vehicle.
No further details were immediately available.
KTLA's Nidia Becerra and Matt Phillips contributed to this report.