The 5 Freeway reopened Thursday night after an hours-long closure due to snow accumulation on the roadway.
Before the major thoroughfare reopened, CHP officials were escorting both vehicle on both sides at 25 mph.
The highway was cleared and fully reopened sometime after 5 p.m., Caltrans officials tweeted. It had previously been closed from Grapevine Road to Parker Road in Castaic.
Snow fell on the major thoroughfare overnight and continued into Thursday afternoon.
The closure came as snow levels dropped to low elevations during a cold Southern California spell.
Forecasters were expecting one to three inches of snow to fall in mountain areas above 2,500 feet, with up to 6 inches possible over the eastern San Gabriel Mountains.
Snow-like conditions were reported from Malibu to Eagle Rock Thursday and from Rancho Cucamonga to Simi Valley.
National Weather Service officials were especially concerned about dangerous driving conditions on mountain roads and highways due to the low snow levels.
Snow and icy conditions also closed other major roads in SoCal.
All highways heading into Big Bear were closed late Thursday morning, according to the National Weather Service in San Diego. "Mud slides and avalanches have been reported on Hwy 38. Stay indoors and avoid traveling in the mountains today," officials tweeted.
In addition, the 5 Freeway was also closed in Primm at the border with Nevada because of "heavy snow conditions." The 15 Freeway is closed through Baker, officials said in a tweet.