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A car crash in Fontana left two people dead after a vehicle driving at a high rate of speed in the wrong direction collided with two other vehicles Wednesday, authorities said. 

At around 3 p.m., a green Ford Expedition driving southbound on Sierra Avenue near Ramona Avenue at a high rate of speed collided with several motorists traveling on the northbound side of the road, Fontana police said.

Police say they received 911 calls about the speeding vehicle but were not able to intercept it before the crash.

Two people were pronounced dead, and three others were transported to a local hospital. Officials said one of the people hospitalized was the driver of the Expedition.

The victims in the hospital are all in critical condition, and one of them is in surgery, police said.

Police have not yet released information on the victims’ identities.

Sources told KTLA a mother and three children were the victims inside of the red vehicle. The mother and a 21-year-old daughter were killed, and the other two children were in critical condition.

The green Expedition crashed into a red vehicle and two white vehicles, authorities said.

Street closures were expected in the area for several hours.

No further details were immediately available.