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A big rig crash on the 5 Freeway left one person dead, another seriously injured and prompted several lane closures just north of Sylmar Thursday morning.

The incident occurred about 11:45 p.m. Wednesday when a big rig headed southbound apparently struck a bridge support column just north of the 210 Freeway, according to the California Highway Patrol’s traffic incident log.

The big rig was in the truck bypass lane when it struck a piling for the overhead 210 overpass, the log stated.

The collision shifted the truck load forward and trapped two people inside the cab, the Los Angeles Fire Department stated. The vehicle was loaded with grapes, some of which spilled on the freeway, CHP’s log stated.

One patient was extricated from the cab and transported to a local hospital in serious condition, according to the Fire Department. The second person was pronounced dead at the scene. Authorities have not identified the individuals involved in the crash.

The collision also sent concrete onto the freeway, prompting officials to close multiple southbound lanes.

All lanes except the truck lane had reopened before noon. The truck lane reopened to traffic by 2 p.m., CHP said.

The cause of the crash is under investigation.