The closure, reported at 4:50 a.m., affects exits 152 (Lankershim Boulevard) and 153A (Sheldon Street).
Traffic was backed up to exit 150B (Sunland Boulevard), the site added.
Traffic is being diverted onto Lankershim Boulevard, the CHP said on X, the site formerly known as Twitter, though as of about 7 a.m., CHP Officer Kendricks said the HOV and No. 1 lanes had reopened.
By about 7:45 a.m., congestion had eased into stop-and-go traffic, causing delays of up to five minutes, according to sigalert.com.
The other lanes are expected to reopen later on Monday.