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Five people were hurt after a collision on the Pacific Coast Highway near Point Mugu in Ventura County sent one vehicle into the water Thursday evening, according to authorities.

The car, which had crashed with one other vehicle, plunged 50 feet into the water, the Ventura County Fire Department said.

The vehicle’s two occupants were ejected and sustained critical injuries,  the agency said. One of them was transported to a trauma center by air and the other taken to a hospital by ground, the Fire Department added.

Two others, one with moderate injuries and another with minor injuries, were taken to the hospital on ground as well, the agency said. A fifth patient refused to be taken to a medical center, authorities said.

Three pedestrians were hit in the incident, according to officials.

The southbound lanes on State Route 1 were shut down from Las Posas Road for near two hours but reopened around 10:30 p.m., the California High Patrol said.

Correction: An earlier version of this story incorrectly stated the number of patients taken to the hospital.