Protesters were pepper-sprayed and three were arrested as hundreds marched to Trump Tower in New York on Saturday.
The large crowd of demonstrators gathered in Manhattan to march from Columbus Circle near Central Park to Trump Tower on Fifth Avenue.
Some supporters of GOP presidential candidate front-runner Donald Trump were at the rally, but the majority of the crowd appeared to include protesters.
A small skirmish erupted when protesters allegedly started throwing water bottles at police, who were trying to keep them from impeding traffic, CNN reported.
A handful of protesters were pepper-sprayed and three were arrested on suspicion of disorderly conduct, a New York police spokesman told CNN.
Hundreds of protesters marched, and some carried signs with messages such as “#CrushTrump,” “Liar Liar Pants on Fire, Only Hatred You Inspire,” and “We Love Immigrant Apparel,” video form KTLA sister station PIX11 showed.
Chants included, “Hey, hey / ho, ho / Donald Trump has got to go,” and “Trump Trump go away / racist, sexist, anti-gay.”
By mid-afternoon, “#CrushTrump” was trending on Twitter with nearly 30,000 published tweets including the hashtag.
The march was organized by groups that included immigrant-rights activists and the “Cosmopolitan Antifascists,” CNN reported.
A Facebook page for the group said it stands for “inclusion, diversity and human rights.”
One protester, Malu Huacuja, who is Mexican, said she was protesting Trump’s rhetoric on immigration.
“I am not a drug dealer,” she said. “I am not a criminal. I am not a rapist … Hatred is a very dangerous poison in the soul of humanity.”
Also on Saturday, dozens of protesters blocked traffic near a Trump event in Arizona, causing traffic to be backed up for miles.